The BioStem difference is defined by harnessing the power of Nature and Science with superior integrity.
This results in compelling Clinical Evidence that health care professionals can respect and patients can experience.
BIOSTEM TECHNOLOGIES CONTINUES TO INVEST IN EXPANDING ITS LIBRARY OF CLINICAL EVIDENCE SUPPORTING THE USE OF ITS PROPRIETARY ALLOGRAFTS.
Intended for use as a wound covering, barrier membrane, conduit, and/or cushion.

Advanced Surgical Care
- Reconstruction
- Nerve Repair
- Traumatic Wounds
- Bone & Joint Reconstruction
- Fractures & Nonunions
- Cartilage Repair
- Soft Tissue Repair
- Spinal Decompression
Advanced Wound Care
- Post-surgical Wound Dehiscence
- Venous Leg Ulcers
- Chronic Wounds
- Arterial Ulcers
- Burns
- Diabetic Foot Ulcers

The real, and most important, outcome is improving patients’ lives.
With an extensive history of research and development in human birth tissue, BioStem has built an extensive clinical evidence library supporting its proprietary perinatal tissue allografts.
Learn More by accessing our comprehensive Clinical Evidence Library, via our Physician Portal.
BIOSTEM TECHNOLOGIES ALLOGRAFTS ARE USED IN A WIDE ARRAY OF SURGICAL AND WOUND APPLICATIONS:
Intended for use as a wound covering, barrier membrane, conduit, and/or cushion.
A multicentre, randomized, controlled clinical trial assessing cryopreserved ultra-thick human amniotic membrane in the treatment of complex diabetic foot ulcers. Wound Repair Regen. 2025, 33 (6):e70110. Caporusso J, Motley T, Lantis JC II, et al.
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A prospective, multicentre, randomized, controlled trial of non-healing diabetic foot ulcers treated with standard care with or without BR-AC: top-line results. The International Journal of Tissue Repair, 2025. McCoy N., Weston WW. et al.
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One-year safety, healing, and amputation rates of Wagner 3-4 diabetic foot ulcers treated with cryopreserved human umbilical cord. Wound Repair and Regenerations. 2020 May 9. Warston WA, Lantis JC, Wu SC, Nouvong A, Clements JR, Lee TD, McCoy ND, Slade HB, Tseng SC.
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A single-center, retrospective review of robot-assisted laparoscopic prostatectomy with and without cryopreserved umbilical cord allograft in improving continence recovery. Journal of Robotic Surgery, Vol 14, pg 283-289, 2020. M. Ahmed, M. Esposito, G. Lavallo.
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An open-label trial of cryopreserved human umbilical cord in the treatment of complex diabetic foot ulcers complicated by osteomyelitis. Wound Repair and Regeneration: The official Publication of the Wound Healing Society and the European Tissue Repair Society, 2019, Marston WA, Lantis JC, Wu SC, et al.
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Use of cryopreserved umbilical cord with negative pressure wound therapy for complex diabetic ulcers with osteomyelitis.
J Wound Care. 2017, 26 (Suppl10):S38-S44. Raphael A, Gonzales J.
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A retrospective study of cryopreserved umbilical cord as an adjunctive therapy to promote the healing of chronic, complex foot ulcers with underlying osteomyelitis. Wound Repair and Regeneration: The Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 2016; 24: 885-93. Caputo WJ, Vaquero C, Monterosa A, et al.
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Assessing placental membrane treatment efficiency in diabetic foot ulcers: Processing for retention versus lamination. Health Science Reports, 7 (6), e2196. 2004. Frykberg, R.G, & Tunylswa, Z.
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EXPLORE OUR TECHNOLOGY AND PRODUCTS FROM THE ABOVE REFERENCED CLINICAL EVIDENCE:
Are you a Health Care Professional and could use more types of clinical support?
BioStem is proud of our extensive clinical evidence library supporting CryoTek and SteriTek processed perinatal tissue allografts. After decades of research, supporting clinical publications and case study evidence, we invite Health Care Professionals to:
Learn More by accessing our comprehensive Clinical Evidence Library, via our Physician Portal.

EVENTS
BioStem is an active supporter of surgical and wound care education and training events.
See where we will be next, presenting our scientific and clinical evidence.
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