Why the Way You Process Amniotic Tissue Matters in Wound Care

In the world of advanced wound care, innovation doesn’t stop at the discovery of effective materials—it extends into how those materials are prepared, preserved, and delivered.

One such innovation is the use of amniotic tissue, derived from donated placentas, as a covering for chronic and acute wounds. However, not all placental tissue allografts are created equal. The difference lies in the process.

At BioStem Technologies, we’ve learned that how you process matters just as much as what you process. That’s why we developed and rely on our proprietary BioREtain™ method—an advanced preservation process that retains the natural integrity of amniotic tissue to support the body’s natural healing cascade.

Not All Allografts Are the Same

Many tissue processors use harsh chemical treatments, irradiation, or dehydration methods that, while effective for sterilization, can destroy key components. These include essential growth factors, extracellular matrix proteins, and cytokines—all of which are critical for wounds to close naturally.

What Makes BioREtain Different

The minimally invasive BioREtain process was designed to preserve the natural integrity of the amniotic tissue. Our gentle and proprietary method avoids harsh chemical washes and high-heat dehydration, enabling us to maintain the viability of the key factors within the tissue.

This translates into an allograft that retains more of the factors that help support the body’s healing cascade. With BioREtain, these factors are preserved in higher concentrations when compared to leading competitors, promoting fewer treatment days and potentially better patient outcomes.

Real Results. Real Impact.

Studies have shown our BioREtain allografts to retain more of the factors than some of the largest competitors in this space.

Click here to see our clinical charts

Conclusion: The Future of Wound Care Is Process-Driven

The conversation around amniotic tissue shouldn’t begin and end with sourcing. It needs to focus on processing. BioREtain is redefining what’s possible in wound care by preserving the power of nature through science and innovation.

So, next time you consider an allograft for your patient, ask not just what it is—but how it was made.

Because wound care isn’t just about coverage. It’s about connection—between science, tissue, and the body’s natural ability to repair.

Doc ID# MKTG-008